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KMID : 0364019930260120972
Korean Journal of Thoracic and Cardiovascular Surgery
1993 Volume.26 No. 12 p.972 ~ p.979
Evaluation of the Extent of the Stenosis in Relation to the Suture Materials and Methods after End-to-End Anastomosis of the Trachea



Abstract
The extent of stenosis of the anastomotic site after complete transection and reanastomosis of the trachea was studied using different suture materials and methods. The trachea was transected at two parts(the upper & the lower)at least 3cm apart
from
each other and reanastomosed by continuous suture in one part and by interrupted suture in the other part with 6-0 vicryl(group 1), with 6-0 polypropylene(group 2) and with 6-0 polydioxanone(PDS) (group 3). Each group contains 7 white rabbits.
The animals were observed for 76 to 104 days (mean, 90 days). Stenosis of the trachea was assessed at the time of induced death. The cross sectional area of each anastomotic site and three normal areas about 1.5cm below the anastomoses were
obtained.
The degree of resultant stenosis was significantly less when a PDS was used than when the other suture materials were used (P<0.025). The use of interrupted sutures proved to be significantly superior to the other method(P<0.025). Histopatologic
studies
were done for all specimens. Vicryl showed marked tissue reaction with inflammatory cell infiltration. But in PDS, there was no fibrosis or inflammatory cell infiltration. Prolene showed little tissue reaction with the persistant suture
materials.
(Korean J Thoracic Cardiovas Surg 1993;26:972-9)
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